Comparison of Ellagic Acid and NSAI Agents in the Treatment of Achilles Tendon Lacerations: An Experimental Study in Rabbits

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ALLAHVERDİ E., ALLAHVERDİ T. D., VURAL S.

INTERNATIONAL SURGERY, cilt.104, sa.11-12, ss.575-581, 2019 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 104 Sayı: 11-12
  • Basım Tarihi: 2019
  • Doi Numarası: 10.9738/intsurg-d-19-00007.1
  • Dergi Adı: INTERNATIONAL SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.575-581
  • Anahtar Kelimeler: Rabbit, Achilles tendon, Ellagic acid, NSAI
  • Ankara Üniversitesi Adresli: Evet

Özet

Objective: Although Achilles tendon ruptures can have many causes, they are known to develop most commonly with trauma. Nonsteroidal anti-inflammatory drugs (NSAID) and low doses of corticosteroids are used in the medical treatment of tendon ruptures. Ellagic acid (EA), which also has an anti-inflammatory effect, has been reported to show its effect via cyclooxygenase 2 (COX2) inhibition as well. The effects of EA and diclofenac sodium on tendon healing were compared in this study.