Akademik Veri Yönetim Sistemi
BMC GERIATRICS, cilt.25, sa.1, 2025 (SCI-Expanded, SSCI, Scopus)
Background Anticholinergic and/or sedative mediations are one of the most commonly prescribed medication groups in older adults. This study aimed to assess the prevalence of anticholinergic and/or sedative mediations use in community dwelling older adults as well as potentially associated factors with their use. Methods A cross sectional study was conducted among community dwelling older adults who accepted invitation for geriatric screening in the Public Education Centres (PEC) in T & uuml;rkiye. The subgroup study population was selected among those who used at least one medication. The prevalence of anticholinergic and/or sedative mediations use, comprehensive geriatric tests, drug-drug interactions and polypharmacy were assessed. Statistical analysis was performed to identify associated factors with anticholinergic and/or sedative mediations use. Results A total of 608 older adults voluntarily participated in the study from the 16 PEC. Among these 372 were eligible (61%). The prevalence of anticholinergic and/or sedative medications use was 36% among the community dwelling older adults. Polypharmacy was present in 32% of the them. Drug-drug interactions involved anticholinergic and/or sedative medications was common (42%). Polypharmacy (p < 0.001) and poor physical function (frailty, p = 0.026; sarcopenia, p = 0.003; instrumental activities of daily living, p = 0.001; and activities of daily living, p = 0.045) were found to be associated with the use of anticholinergic and/or sedative medications in this study. Conclusions With common anticholinergic and/or sedative mediations use and its associated risk for polypharmacy, poor physical function and drug-drug interactions, their use must be balanced with their potential risks and benefits.