Some inherited disorders in pacing horses in Turkey

ÖZBEYAZ C., YÜCEER ÖZKUL B.

ANKARA UNIVERSITESI VETERINER FAKULTESI DERGISI, cilt.69, sa.1, ss.43-49, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 69 Sayı: 1
  • Basım Tarihi: 2022
  • Doi Numarası: 10.33988/auvfd.812189
  • Dergi Adı: ANKARA UNIVERSITESI VETERINER FAKULTESI DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.43-49
  • Anahtar Kelimeler: Horse, pacing, PSSM, SCID, Turkey, POLYSACCHARIDE STORAGE MYOPATHY, SEVERE COMBINED IMMUNODEFICIENCY, GYS1 MUTATION, ESTIMATED PREVALENCE, ARABIAN HORSES, GENE, FREQUENCY, DISEASES, BREEDS
  • Ankara Üniversitesi Adresli: Evet

Özet

This study was carried out to detect the presence of mutant alleles of polysaccharide storage myopathy (PSSM) and severe combined immunodeficiency (SCID) disorders in pacing horses raised in different regions of Turkey. Blood/hair samples from 264 (182 Indigenous, 31 Iranian, 24 Afghan, and 27 Bulgarian) pacing horses aged 4 and over were used. As a result of the study, a mutation-heterozygosis (GA) in the GYS1 gene related to PSSM disease was detected in one of the pacing horses (Bulgarian horse). No deletions were observed in the DNA-PKcs gene region in the pacing horses for SCID disease. This study has been carried out to identify the status of two inherited disorders in pacing horses in Turkey. It was determined that there are no mutant genes in indigenous pacing horses, in terms of PSSM and SCID disorders, which are the major hereditary disorders in horses.