Evaluation of Antioxidant Potential, Anticholinesterase Activity and Element Content of Chlorophyllum rhacodes Spe


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Akata I., Baba H., Kabaktepe Ş., Sevindik M.

PROSPECTS, cilt.55, sa.3, ss.1-7, 2025 (Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 55 Sayı: 3
  • Basım Tarihi: 2025
  • Dergi Adı: PROSPECTS
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.1-7
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Ankara Üniversitesi Adresli: Evet

Özet

rhacodes were evaluated. In order to determine the antioxidant capacity, total antioxidant level (TAS),

total oxidant level (TOS), oxidative stress index (OSI), DPPH radical scavenging activity and FRAP ferric

reducing power analyses were applied. According to the obtained results, TAS value was determined as

3.125±0.060 mmol/L, TOS value as 6.821±0.062 µmol/L, OSI value as 0.218±0.003, DPPH activity as

55.430±1.438 mg TE/g and FRAP value as 72.540±1.461 mg TE/g. These data revealed that C. rhacodes

showed a significant level of antioxidant activity. In the evaluation of anticholinesterase activity,

inhibitory effects against AChE and BChE enzymes were determined and IC₅₀ values were determined as

94.330±1.536 µg/mL and 128.397±1.556 µg/mL, respectively. These results show that C. rhacodes shows

limited inhibitory effect on these enzymes but may have a certain level of anticholinesterase potential.

According to the results of elemental analysis, Cd (14.78±1.53), Cr (33.17±1.42), Mn (7.35±0.52), Cu

(155.77±2.34), Fe (469.30±15.75), Pb (6.98±0.54), Ni (3.66±0.31) and Zn (76.18±2.25) mg/kg levels were

detected in mushroom samples. In particular, it was observed that Cd and Cu levels were above the

upper limits specified in the literature. This situation shows that C. rhacodes tends to accumulate some

heavy metals and may be highly sensitive to environmental pollution. In conclusion, C. rhacodes species

exhibits a biologically remarkable profile with certain antioxidant and anticholinesterase activities and

can also be considered as a potential indicator species in the biological monitoring of environmental

metal expo