Synthesis of highly <i>N</i>-substituted indole library via conjugate additions of indoline and their synthetic tool potentials

KILIÇ, Haydar; Bayindir, Sinan; Erdogan, Esra; SARAÇOĞLU, NURULLAH

doi:10.1016/j.tet.2012.04.066

Synthesis of highly <i>N</i>-substituted indole library via conjugate additions of indoline and their synthetic tool potentials

KILIÇ H., Bayindir S., Erdogan E., SARAÇOĞLU N.

TETRAHEDRON, cilt.68, sa.27-28, ss.5619-5630, 2012 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 68 Sayı: 27-28
Basım Tarihi: 2012
Doi Numarası: 10.1016/j.tet.2012.04.066
Dergi Adı: TETRAHEDRON
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Index Chemicus (IC)
Sayfa Sayıları: ss.5619-5630
Ankara Üniversitesi Adresli: Hayır

Özet

A comprehensive library of N- or 1-substituted indoles was formed by conjugate additions of indoline with Michael acceptors followed by an oxidation step. Using N-substituted indoles as key Michael donors, the synthesis of 1,3-disubstituted indoles was also accomplished. (c) 2012 Elsevier Ltd. All rights reserved.