Effects of Water Soluble Garlic Extract on Human Leukemia HL60 Cell Lines

İşgör Y. G., Iscan M., Öztürk H. S., Durak İ.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.33, no.3, pp.78-84, 2008 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 3
  • Publication Date: 2008
  • Journal Name: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.78-84
  • Keywords: Allium sativum, water soluble garlic extract, acute promyeloctic leukemia, antioxidant defense, SUPEROXIDE-DISMUTASE, DIALLYL DISULFIDE, ACTIVATION, APOPTOSIS, GENERATION, INDUCTION, ADDUCTS
  • Ankara University Affiliated: Yes

Abstract

Purpose: Studies with garlic have shown the medicinal value of the plant by its antioxidant potential which is exerted by its organosulfur rich content. In this study, the aim is to determine any potential antioxidant efficacy of the less toxic water soluble extract of a widely cultivated garlic form in Turkey, in terms of alterations on the oxidant/antioxidant status of HL60 promyelocytic leukemia cell line.