Phospholipid fatty acid composition of rat, rabbit, human and dog plasma
Ankara Universitesi Eczacilik Fakultesi Dergisi, cilt.32, sa.2, ss.99-112, 2003 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 32 Sayı: 2
- Basım Tarihi: 2003
- Dergi Adı: Ankara Universitesi Eczacilik Fakultesi Dergisi
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.99-112
- Anahtar Kelimeler: Plasma phospholipid fatty acids, Species
- Ankara Üniversitesi Adresli: Evet
Özet
The purpose of this study was to investigate and compare the fatty acids of plasma phospholipids in rat, rabbit, human and dog. The prominent fatty acids of phospholipids in the species were C16:0, C18:0, C18:1, C18:2 and C20:4. Fatty acids generally decreased in the following order: SFA (Saturated fatty acids)>MUFA (monounsaturated fatty acid)>PUFA (polyunsaturated fatty acid) with little, exceptions. PUFA was higher in PE (phosphatidyl ethanolamine) and PC (phosphatidyl choline) and PUFA>MUFA in rabbit and human plasma, whereas PUFA was higher in PC and PS in dog and in PI, PC and SPH in rat. C 18:1 was higher than the other MUFA.. Among PUFA C18:2 was higher and arachidonate (C20:4) was lower in rabbit compared to other species. C18:2 was major PUFA and C20:4 was the second one mainly in PC and PE and followed by PS (phosphatidyl serine), PI (phosphatidyl inositol) and SPH (sphingomyelin) in all of the species. Others (C20:2, C18:3, C20:3 and C20:5) were less than % 0.1 in dog and also present in very small amounts in rat. These PUFA were present in PE and PC in rabbit and as well as in the other phospholipids in human. LCPUFAs (long chain polyunsaturated fatty acids)were not present in dog and rat had small amouts of C22:4 in PC.