Osteopontin is a Prognostic Factor in Patients with Advanced Gastric Cancer

YAZICI O., Dogan M., Ozal G., AKTAŞ S. H., Demirkazik A., UTKAN G., ...Daha Fazla

COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, cilt.24, sa.8, ss.1229-1235, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 24 Sayı: 8
  • Basım Tarihi: 2021
  • Doi Numarası: 10.2174/1386207323666200902135349
  • Dergi Adı: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.1229-1235
  • Anahtar Kelimeler: Gastric cancer, predictive factor, prognostic factor, Osteopontin, biomarker, oncologist, CELL-PROLIFERATION, DOWN-REGULATION, TUMOR-MARKERS, BREAST, EXPRESSION, BIOMARKER, CHEMOTHERAPY, ANGIOGENESIS, SENSITIVITY, RESISTANCE
  • Ankara Üniversitesi Adresli: Evet

Özet

Objective: Osteopontin (OPN), a phosphorylated sialoprotein, has been shown to overex-press in a variety of cancers and to contribute tumor progression and metastasis by increasing cell migration and adhesion. In the current study, we aimed to investigate the prognostic and predictive role of OPN in patients with advanced gastric cancer.