Papillary microcarcinomas of the thyroid gland and immunohistochemical analysis of expression of p53 protein in papillary microcarcinomas

Corapcioglu, Demet; SAK, SERPİL; Delibasi, Tuncay; Tonyukuk, Vedia; Kamel, Nuri; Uysal, Ali; Kocak, Savas; Aydintug, Semih; Erdogan, Gurbuz

doi:10.1186/1479-5876-4-28

Papillary microcarcinomas of the thyroid gland and immunohistochemical analysis of expression of p53 protein in papillary microcarcinomas

Corapcioglu D., SAK S., Delibasi T., Tonyukuk V., Kamel N., Uysal A. R., ...Daha Fazla

JOURNAL OF TRANSLATIONAL MEDICINE, cilt.4, 2006 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 4
Basım Tarihi: 2006
Doi Numarası: 10.1186/1479-5876-4-28
Dergi Adı: JOURNAL OF TRANSLATIONAL MEDICINE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Ankara Üniversitesi Adresli: Evet

Özet

Background: Thyroid papillary microcarcinoma (TPM) is defined according to WHO criteria as a thyroid tumor smaller than 1 - 1.5 cm. TPMs are encountered in 0.5 - 35.6 % of autopsies or surgical specimens where carcinoma had been unsuspected. The purpose of the present study was to evaluate patients who had TPMs in terms of clinical findings, histopathological features and immunohistochemical evidence of expression of the tumor suppressor gene p53.