Incidental Thyroid Uptake on 18F-FES PET/CT Revealing Papillary Thyroid Carcinoma


Akkus Gunduz P., Cidemal M., GÖKÇAY CANPOLAT A., SOYDAL Ç.

Clinical Nuclear Medicine, 2026 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2026
  • Doi Numarası: 10.1097/rlu.0000000000006691
  • Dergi Adı: Clinical Nuclear Medicine
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Anahtar Kelimeler: 18F-FES, papillary thyroid carcinoma, PET/CT, thyroid incidentaloma
  • Ankara Üniversitesi Adresli: Evet

Özet

A 70-year-old woman with endometrial carcinoma underwent 18F-FDG and 18F-FES PET/CT for pretreatment evaluation. Both studies demonstrated focal uptake in a nodule at the inferior pole of the left thyroid lobe. Ultrasonography revealed a TI-RADS 3 nodule, and fine-needle aspiration cytology showed atypia of undetermined significance. Total thyroidectomy was performed, and histopathology revealed a 20-mm noninvasive encapsulated classic papillary thyroid carcinoma. Estrogen receptor (ER) immunohistochemistry was unavailable; therefore, the relationship between 18F-FES uptake and ER expression could not be assessed. The patient subsequently received 100 mCi of radioactive iodine.