An infantile Cushing syndrome due to misuse of topical steroid


ŞIKLAR Z., Bostanci I., Atli O., Dallar Y.

PEDIATRIC DERMATOLOGY, vol.21, no.5, pp.561-563, 2004 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 21 Issue: 5
  • Publication Date: 2004
  • Doi Number: 10.1111/j.0736-8046.2004.21508.x
  • Journal Name: PEDIATRIC DERMATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.561-563
  • Ankara University Affiliated: Yes

Abstract

Chronic low-dose exogenous steroid therapy in children can result in hypothalamic-pituitary-adrenal axis dysfunction. However, the development of Cushing syndrome from topical steroid therapy is unusual. A 9-month-old girl with a diagnosis of Cushing syndrome caused by long-term topical clobetasol propionate application was evaluated. The patient was found to have severe adrenal suppression. Limiting the use of steroid-containing drugs, prescription of less potent agents, especially during infancy, and warning of parents about potential side effects are very important.