The effect of BRAF(V)(600E) mutation on lymph node involvement in papillary thyroid cancer

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Sahin S., Daglar G., Menekse E., Cavdarli B., BAĞLAN T.

TURKISH JOURNAL OF SURGERY, vol.36, no.3, pp.249-255, 2020 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 36 Issue: 3
  • Publication Date: 2020
  • Doi Number: 10.47717/turkjsurg.2020.4696
  • Journal Name: TURKISH JOURNAL OF SURGERY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.249-255
  • Keywords: BRAF, Lymph node, involvement, papillary thyroid cancer, BRAF(V600E) MUTATION, HIGH PREVALENCE, BRAF MUTATION, CARCINOMA, MANAGEMENT, TUMOR, METASTASIS, DISSECTION, DIAGNOSIS, PATHWAY
  • Ankara University Affiliated: Yes

Abstract

Objective: Papillary thyroid cancer (PTC) is the most common well-differentiated thyroid cancer. Lymph node (LN) metastasis is frequently seen in PTC. The effect of BRAF(V600E) mutation on PTC-associated LN metastasis has not been clearly established. Therefore, we aimed to evaluate the effect of the BRAF(V600E) mutation in patients with PTC on regional LN metastasis.