The effect of BRAF(V)(600E) mutation on lymph node involvement in papillary thyroid cancer


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Sahin S., Daglar G., Menekse E., Cavdarli B., BAĞLAN T.

TURKISH JOURNAL OF SURGERY, cilt.36, sa.3, ss.249-255, 2020 (ESCI, Scopus, TRDizin) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 36 Sayı: 3
  • Basım Tarihi: 2020
  • Doi Numarası: 10.47717/turkjsurg.2020.4696
  • Dergi Adı: TURKISH JOURNAL OF SURGERY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.249-255
  • Anahtar Kelimeler: BRAF, Lymph node, involvement, papillary thyroid cancer, BRAF(V600E) MUTATION, HIGH PREVALENCE, BRAF MUTATION, CARCINOMA, MANAGEMENT, TUMOR, METASTASIS, DISSECTION, DIAGNOSIS, PATHWAY
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Ankara Üniversitesi Adresli: Evet

Özet

Objective: Papillary thyroid cancer (PTC) is the most common well-differentiated thyroid cancer. Lymph node (LN) metastasis is frequently seen in PTC. The effect of BRAF(V600E) mutation on PTC-associated LN metastasis has not been clearly established. Therefore, we aimed to evaluate the effect of the BRAF(V600E) mutation in patients with PTC on regional LN metastasis.