Continuous venovenous hemodiafiltration in the treatment of newborns with an inborn metabolic disease: a single center experience

Akduman H., OKULU E., EMİNOĞLU F. T., KENDİRLİ T., TUNÇ G., Azapagasi E., ...More

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.50, no.1, pp.12-17, 2020 (SCI-Expanded, Scopus, TRDizin) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 50 Issue: 1
  • Publication Date: 2020
  • Doi Number: 10.3906/sag-1811-8
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.12-17
  • Keywords: Inborn metabolic diseases, renal replacement therapy, continuous venovenous hemodiafiltration, newborn, survival, RENAL REPLACEMENT THERAPY, CONTINUOUS ARTERIOVENOUS HEMOFILTRATION, PERITONEAL-DIALYSIS, ERRORS, CHILDREN, HYPERAMMONEMIA, HEMODIALYSIS, MANAGEMENT, FAILURE, THROMBOCYTOPENIA
  • Ankara University Affiliated: Yes

Abstract

Background/aim: Most inborn metabolic diseases are diagnosed during the neonatal period. The accumulation of toxic metabolites may cause acute metabolic crisis with long-term neurological dysfunction and death. Renal replacement therapy (RRT) modalities allow the efficient removal of toxic metabolites. In this study, we reviewed our experience with continuous venovenous hemodiafiltration (CVVHDF) as RRT for newborns with an inborn metabolic disease.