Diagnostic Dilemma of Lactic Acidosis in an Infant After Liver Transplant: A Case Report

KAHVECİ F., GÜN E., BALABAN B., Ucmak H., TUNA KIRSAÇLIOĞLU C., BALCI D., ...Daha Fazla

Experimental and Clinical Transplantation, cilt.21, sa.7, ss.623-625, 2023 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 7
  • Basım Tarihi: 2023
  • Doi Numarası: 10.6002/ect.2021.0249
  • Dergi Adı: Experimental and Clinical Transplantation
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.623-625
  • Anahtar Kelimeler: Energy metabolism, Parenteral nutrition, Thiamine deficiency
  • Ankara Üniversitesi Adresli: Evet

Özet

Thiamine is the cofactor of many enzymes involved in energy metabolism. Patients under total parenteral nutrition are at risk for thiamine deficiency if there is renal thiamine loss or increased thiamine requirements to mitigate systemic diseases. Thiamine deficiency symptoms include seizures, neuropathy, ataxia, peripheral vasodilation, myocardial insufficiency, sudden collapse, and death. In this report, we present an infant liver transplant recipient with progressive lactic acidosis that responded well to thiamine replacement to mitigate a lack of thiamine in total parenteral nutrition.