Homozygosity for the HR2 haplotype: Is it a risk factor for thrombosis?


Ulu A., YILMAZ E., Akar E., Akar N.

Turkish Journal of Haematology, vol.20, no.4, pp.213-215, 2003 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 20 Issue: 4
  • Publication Date: 2003
  • Journal Name: Turkish Journal of Haematology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.213-215
  • Keywords: A4070G, Haplotype, HR2, Polymorphism, Thromboemobolism
  • Ankara University Affiliated: Yes

Abstract

A4070G (His 1299 Arg) polymorphism in exon 13 of factor V gene can influence factor V levels and contribute to the activated protein C resistance. We are presenting our data concerning Turkish population and postulate that homozygosity for the HR2 haplotype may be an important risk factor for thrombosis.