Homozygosity for the HR2 haplotype: Is it a risk factor for thrombosis?

Ulu A., YILMAZ E., Akar E., Akar N.

Turkish Journal of Haematology, cilt.20, sa.4, ss.213-215, 2003 (SCI-Expanded, Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 4
  • Basım Tarihi: 2003
  • Dergi Adı: Turkish Journal of Haematology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.213-215
  • Anahtar Kelimeler: A4070G, Haplotype, HR2, Polymorphism, Thromboemobolism
  • Ankara Üniversitesi Adresli: Evet

Özet

A4070G (His 1299 Arg) polymorphism in exon 13 of factor V gene can influence factor V levels and contribute to the activated protein C resistance. We are presenting our data concerning Turkish population and postulate that homozygosity for the HR2 haplotype may be an important risk factor for thrombosis.