Skin Localization of Lipid Nanoparticles (SLN/NLC): Focusing the Influence of Formulation Parameters

AMASYA, GÜLİN; Sandri, Giuseppina; BEŞİKCİ, ARZU; BADILLI, FAHRİYE; Caramella, Carla; Bonferoni, Maria; Tarimci, Nilufer

doi:10.2174/1567201813666160104130505

Skin Localization of Lipid Nanoparticles (SLN/NLC): Focusing the Influence of Formulation Parameters

AMASYA G., Sandri G., BEŞİKCİ A., BADILLI F. U., Caramella C., Bonferoni M. C., ...Daha Fazla

CURRENT DRUG DELIVERY, cilt.13, sa.7, ss.1100-1110, 2016 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 13 Sayı: 7
Basım Tarihi: 2016
Doi Numarası: 10.2174/1567201813666160104130505
Dergi Adı: CURRENT DRUG DELIVERY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1100-1110
Anahtar Kelimeler: Confocal microscopy, dermal drug delivery, fluorescein, hydrophilic drug, lipid nanoparticles, NLC, SLN, DRUG-DELIVERY, CARRIERS NLC, IN-VITRO, TOPICAL DELIVERY, PENETRATION, CANCER, 5-FLUOROURACIL, COENZYME-Q10, SYSTEMS, CELLS
Ankara Üniversitesi Adresli: Evet

Özet

Background: In this study, fluorescein labeled SLN and NLC formulations were prepared for improving the dermal distribution of the hydrophilic active ingredients and for enhancing the skin penetration.