Transabdominal ultrasound–guided oocyte retrieval for oocyte cryopreservation using a vaginal probe: a comparison of applicability, effectiveness, and safety with conventional transvaginal approach

Sönmezer M., Saçıntı K. G., Gülümser Ç., Özkavukçu S., Atabekoğlu C., ŞÜKÜR Y. E., ...More

Journal of Assisted Reproduction and Genetics, vol.40, no.2, pp.399-405, 2023 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 40 Issue: 2
  • Publication Date: 2023
  • Doi Number: 10.1007/s10815-022-02705-8
  • Journal Name: Journal of Assisted Reproduction and Genetics
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, ATLA Religion Database, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.399-405
  • Keywords: In vitro fertilization, Oocyte cryopreservation, Oocyte retrieval, Transabdominal follicular retrieval, IN-VITRO FERTILIZATION, UNDERWENT RADICAL HYSTERECTOMY, PSYCHOLOGICAL DISTRESS, FOLLICULAR ASPIRATION, SURROGATE PREGNANCY, PATIENT, TRANSPOSITION, INFERTILITY
  • Ankara University Affiliated: Yes

Abstract

© 2023, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.Purpose: We aimed to compare the feasibility, effectiveness, and safety of transabdominal ultrasound–guided oocyte retrieval (TUGOR) using a vaginal probe and traditional vaginal approach in virgin patients undergoing oocyte cryopreservation. Methods: A total of 116 virgin patients who underwent transabdominal ultrasound–guided oocyte retrieval using a vaginal ultrasound probe and 33 patients matched for BMI, antral follicle count, age, day 3 FSH, estradiol, and AMH who underwent vaginal approach were enrolled. Mean number of total oocytes collected, mean number of cryopreserved MII oocytes, duration of the procedure, duration of stimulation, mean gonadotropin consumption, mature oocyte ratio, and a modified follicle-oocyte index were compared between the groups. Results: No statistical difference was found between the groups in mean number of follicles > 12 mm (4.62 ± 4.54 vs. 5.44 ± 4.52), mean number of oocytes collected (4.44 ± 4.14 vs. 5.33 ± 4.52), mean number of cryopreserved MII oocytes (4.01 ± 3.67 vs. 4.53 ± 4.13), mean duration of the procedure (12.4 ± 1.2 vs. 13.4 ± 1.6 min), mean days of stimulation (8.05 ± 1.91 vs. 8.35 ± 1.72 days), mean gonadotropin consumption (1507.9 ± 475.3 vs. 1571.74 ± 404.6 units), mature oocyte ratio (0.78 ± 0.24 vs. 0.82 ± 0.26), and modified follicle oocyte index (0.86 ± 0.63 vs. 0.84 ± 0.19). In the TUGOR group, superficial epigastric artery injury occurred in two patients and resolved spontaneously. Conclusion: Transabdominal oocyte retrieval using a vaginal ultrasound is a safe, effective, and feasible method of oocyte retrieval in some selected patient groups.