The evaluation of epigallocatechin gallate and N-acetylcysteine on serum testosterone levels in male guinea pigs expose to cell phone microwave

KISMALI G., Ozgur E., Sayiner S., Alpaslan B., Guler G., Seyhan N., ...Daha Fazla

Journal of Animal and Veterinary Advances, cilt.8, sa.6, ss.1149-1151, 2009 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8 Sayı: 6
  • Basım Tarihi: 2009
  • Dergi Adı: Journal of Animal and Veterinary Advances
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1149-1151
  • Anahtar Kelimeler: Cell phone, Epigallocatechin gallate, Guinea pig, N-Acetylcysteine, Testosterone
  • Ankara Üniversitesi Adresli: Evet

Özet

Recently, there has been a few information on the effects of mobile phone-exposed on reproduction. The aim of this study to determine the effects of antioxidants namely EGCG and NAC on the serum testosteron levels in the cell phone-exposed guinea pigs. Three-months-old male Guinea pigs were randomized into 6 groups; sham group, not exposed to mobile phone, NAC administration group (300 mg kg-1 i.p. during 7days), 20 min mobile phone-exposed group with NAC administration, 20 min mobile phone-exposed group, EGCG administration group (25 mg kg-1 i.p. during 7 days) and 20 min mobile phone-exposed group with EGCG administration. During the exposure of every guinea pig, external E fields were measured by NARDA EMR 300 and type 8.3 probe. Guinea pigs were exposed to RFR averaged as 11.2±0.5 V m-1 for 20 min a day during 7 days. Serum testosterone levels were analysed by ELISA. The serum testosterone levels were found insignificantly increased in mobile phone-exposed group compared to the control and the other groups (p>0.05). Likewise, the serum testosterone levels were not found significantly different in the N-Acetyl L-Cysteine (NAC) and Epigallocatechin Gallate (EGCG) administrated groups compared to the sham group. © Medwell Journals, 2009.