Factor V 1691 G-A (Leiden) polymorphism and cancer-related venous thromboembolism: a meta-analysis of published studies

Eroglu A., Karasoy D. S., Eroglu N., Akar N.

JOURNAL OF BUON, vol.13, no.1, pp.61-64, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 1
  • Publication Date: 2008
  • Journal Name: JOURNAL OF BUON
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.61-64
  • Keywords: cancer, factor V Leiden, meta-analysis, thrombosis, FACTOR-V-LEIDEN, ACTIVATED PROTEIN-C, ONCOLOGY PATIENTS, BLOOD-DONORS, MUTATION, THROMBOSIS, PREVALENCE, RESISTANCE, RISK, G20210A
  • Ankara University Affiliated: Yes

Abstract

Purpose: Although one of the most common genetic polymorphisms that predispose to venous thromboembolism (VTE) is factor V 1691 G-A (Factor V Leiden; FVL), the effect of this polymorphism on the development of VTE in cancer patients is unclear We have therefore performed a meta-analysis to estimate the risk of VTE associated with FVL among cancer patients.