The Protective Effect of Omeprazole Against Traumatic Brain Injury: An Experimental Study

Ozay R., Turkoglu M. E., Gurer B., Dolgun H., EVİRGEN O., ERGÜDER B. İ., ...Daha Fazla

WORLD NEUROSURGERY, cilt.104, ss.634-643, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 104
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1016/j.wneu.2017.04.136
  • Dergi Adı: WORLD NEUROSURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.634-643
  • Anahtar Kelimeler: Antioxidants, Apoptosis, Methylprednisolone, Neuroprotection, Omeprazole, Traumatic brain injury, ARYL-HYDROCARBON RECEPTOR, CORTICAL IMPACT INJURY, NITRIC-OXIDE, OXIDATIVE STRESS, LIPID-PEROXIDATION, DIOXIN RECEPTOR, ANTIOXIDANT, DEATH, RATS, MITOCHONDRIA
  • Ankara Üniversitesi Adresli: Evet

Özet

BACKGROUND: The development of secondary brain injury via oxidative stress after traumatic brain injury (TBI) is a well-known entity. Consequently, the aim of the present study was to evaluate the role of omeprazole (OM) on rat model of TBI.