A feasible shortcut for the mobilization outcome: Steady state CD34 positive hematopoietic stem cells

YÜKSEL M., Tekgunduz E., Sonmez C., TOPÇUOĞLU P., Yurtcu A., Demiriz I., ...Daha Fazla

TRANSFUSION AND APHERESIS SCIENCE, cilt.47, sa.1, ss.67-75, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 1
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1016/j.transci.2012.05.003
  • Dergi Adı: TRANSFUSION AND APHERESIS SCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.67-75
  • Anahtar Kelimeler: Steady state CD34, Stem cell, Mobilization, Multiple myeloma, Lymphoma, NON-HODGKINS-LYMPHOMA, MULTIPLE-MYELOMA, BLOOD, COLLECTION, TRANSPLANTATION, CHEMOTHERAPY, ENUMERATION, CIRCULATION, CD34+CELLS, PREDICTS
  • Ankara Üniversitesi Adresli: Evet

Özet

Predicting success of hematopoietic cell mobilization is an important issue for transplant physicians. We examined the steady state peripheral blood CD34+ cell count to predict ability to mobilize adequate hematopoietic progenitor cells in 63 myeloma and lymphoma patients. The median steady state CD34+ cell number was 1.56/mu L (0.03-5.76). Although counting steady state CD34+ is definitely cost effective to predict the successful mobilization, we could not find a threshold steady state CD34 count of any value predicting successful mobilization. (C) 2012 Elsevier Ltd. All rights reserved.