Non-enzymatic monitoring of hydrogen peroxide using novel nanosensor based on CoFe2O4@CdSeQD magnetic nanocomposite and rifampicin mediator

Mollarasouli F., KURBANOĞLU S., Asadpour-Zeynali K., Ozkan S. A.

Analytical and Bioanalytical Chemistry, cilt.412, sa.21, ss.5053-5065, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 412 Sayı: 21
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1007/s00216-019-02306-y
  • Dergi Adı: Analytical and Bioanalytical Chemistry
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Agricultural & Environmental Science Database, Aqualine, Aquatic Science & Fisheries Abstracts (ASFA), Artic & Antarctic Regions, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chimica, Communication Abstracts, Compendex, EMBASE, Food Science & Technology Abstracts, MEDLINE, Metadex, Pollution Abstracts, Veterinary Science Database, DIALNET, Civil Engineering Abstracts
  • Sayfa Sayıları: ss.5053-5065
  • Anahtar Kelimeler: CoFe2O4@CdSeQDs magnetic nanocomposite, Rifampicin, Hydrogen peroxide, Electrochemical detection, Glassy carbon electrode, ELECTROCHEMICAL SENSOR, GRAPHENE OXIDE, H2O2, NANOPARTICLES, BIOSENSOR, FABRICATION, HYDROXIDE, ELECTRODE, GLUCOSE, DOTS
  • Ankara Üniversitesi Adresli: Evet

Özet

© 2020, Springer-Verlag GmbH Germany, part of Springer Nature.In this work, a novel strategy was introduced to develop a non-enzymatic hydrogen peroxide (H2O2) sensor based on rifampicin (RIF) electrodeposited on a polyvinylpyrrolidone (PVP)-capped CdSe quantum dot (CdSeQD), CoFe2O4 magnetic nanoparticle–modified glassy carbon electrode (CoFe2O4@CdSeQDs/RIF/GCE). CoFe2O4@CdSeQD magnetic nanocomposite (CoFe2O4@CdSeQD MNCs) was synthesized by a chemical co-precipitation method and characterized by scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), Fourier-transform infrared spectroscopy (FTIR), and X-ray diffraction (XRD). To prepare the non-enzymatic H2O2 sensor, firstly, the glassy carbon electrode surface was modified by dropping 10 μL of 5 mg mL−1 CoFe2O4@CdSeQD MNCs. Then, rifampicin was electrodeposited on the activated CoFe2O4@CdSeQDs/GCE by applying a potential of − 0.7 V for 400 s in pH 2.0 phosphate buffer containing 190 μM of rifampicin. Cyclic voltammetry and electrochemical impedance spectroscopy was used to investigate the electrochemical behavior of this sensor and was used for the reduction of H2O2. Construction of the calibration plot for H2O2 was performed using an amperometric method (− 0.2 V vs. Ag/AgCl) at the modified electrode. Two linearity ranges were obtained from 7 to 145 μM and 145 μM to 1.43 mM with sensitivities of 143.01 μA mM−1 and 28.67 μA mM−1 for the first and second linearity ranges, respectively. The detection limit was obtained as 0.38 μM (S/N = 3). Finally, the reliability of the nanosensor was confirmed with real sample analysis in different beverages such as juice and milk with satisfactory recovery results.