HYPERTROPHIC RESPONSE OF LOWER EXTREMITY MUSCLES TO DIFFERENT RESISTANCE TRAINING INTENSITIES: A META-ANALYSIS AND META-REGRESSION HIPERTROFIČNI ODGOVOR MIŠIC SPODNJIH OKONČIN NA RAZLIČNE INTENZITETE TRENINGA ZA MOČ: META-ANALIZA IN META-REGRESIJA


Eyipinar C. D., Buzdağli Y., KARAYİĞİT R.

Kinesiologia Slovenica, cilt.31, sa.2, ss.85-109, 2025 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 2
  • Basım Tarihi: 2025
  • Doi Numarası: 10.52165/kinsi.31.2.85-109
  • Dergi Adı: Kinesiologia Slovenica
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Sayfa Sayıları: ss.85-109
  • Anahtar Kelimeler: knee extensors, Muscle hypertrophy, muscle thickness, quadriceps femoris
  • Ankara Üniversitesi Adresli: Evet

Özet

This study evaluates the effectiveness of different resistance training intensities (high, moderate, and low) on quadriceps femoris muscle hypertrophy in healthy adults. A literature search was conducted in January 2023 using multiple databases, including Web of Science, SPORTDiscus, Embase, and PubMed. The methodological quality of the studies was assessed using the TESTEX scale. A total of 22 studies with 519 participants were included in this meta-analysis. Statistical analysis, performed using ReviewManager 5.2, showed that all resistance training intensities led to hypertrophy in the quadriceps femoris muscle compared to control or pretest values. High-intensity training resulted in a muscle thickness increase of 2.3 mm (95% CI: 2.21-2.38), moderate-intensity training led to an increase of 1.88 mm (95% CI: 1.74-2.02), and low-intensity training showed an increase of 10.92 mm (95% CI: 10.77-11.08), all with p<.001. Meta-regression analysis revealed a significant relationship between training intensity and hypertrophy in the vastus intermedius (β=0.01, p=0.05, R²=0.56) and vastus lateralis (β=0.01, p=0.007, R²=0.34). However, no significant effect was found for the rectus femoris (β=0.03, p=0.417, R²=0.04) or vastus medialis (β=0.003, p=0.895, R²=0.002). In conclusion, resistance training at different intensities promotes hypertrophy across all quadriceps muscles, with variations depending on the specific muscle group. Meta-regression suggests that every 10% increase in training intensity corresponds to a 0.1 mm increase in vastus intermedius hypertrophy. No significant effect of training intensity was observed for the vastus lateralis, vastus medialis, or rectus femoris muscles.