A comparative study between fine needle aspiration biopsy (FNAB) findings and histopathology in the evaluation of canine skin and skin adnexal tumors


YUMUŞAK N., KUTSAL O.

ANKARA UNIVERSITESI VETERINER FAKULTESI DERGISI, cilt.63, sa.4, ss.393-400, 2016 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 63 Sayı: 4
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1501/vetfak_0000002759
  • Dergi Adı: ANKARA UNIVERSITESI VETERINER FAKULTESI DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.393-400
  • Anahtar Kelimeler: Cytopathology, dog, fine needle aspiration biopsy, histopathology, skin tumours, MALIGNANT PILOMATRICOMA, SUBCUTANEOUS MASSES, MAMMARY-TUMORS, 3 DOGS, NEOPLASMS, CYTOLOGY, REGISTRY, CANCER, DIAGNOSIS, CATS
  • Ankara Üniversitesi Adresli: Evet

Özet

The material of this study was, cytopathologic and histopathologic specimens obtained from 43 of dogs suffering from skin tumors. Samples were submitted by Ankara University, Faculty of Veterinary Medicine or private clinics of veterinary in Ankara. Cytologic specimens were prepared by fine needle aspiration biopsy (FNAB) technique and stained with May-Grunwald Giemsa (MGG). For histopathologic examinations tissue samples were obtained by surgery. Samples were fixed in 10% neutral formalin solution and embedded in paraffin by routine procedures and stained with Hematoxylin-Eosin (H&E). Tumors were obtained from 29 male dogs and 14 female dogs. The age with highest incidence in dogs was between 8 and 15. The breeds of dogs more frequently affected were 14 terrier, 14 mongrel and 15 another different breeds. Localizations of tumors were in the followed regions, head, perianal regions and legs. Cytopathologically, 30 (69,76%) malignant epithelial tumors, 5 (11,62%) benign epithelial tumors, 6 (13,95%) suspect epithelial tumors and 2 (4,65%) few malignant epithelial tumors were diagnosed. Histopathological diagnosis determined 12 (27,9%) squoamous cell carcinoma, 9 (20,9%) hepatoid gland tumours, 7 (16,3%) basal cell carcinoma, 7 (16,3%) sweat gland tumours, 5 (11,6%) sebaceous gland tumours, 2 (4,7%) papilloma and 1 (2,3%) malignant pilomatricoma. The diagnoses were in agreement cytopathologically and histopathologically in 86,05% of cases. The results obtained in the present study suggest that cytopathology is a practical tool for the early diagnosis of canine skin tumours.