An effective and sensitive stability-indicating chromatographic approach based on HPLC for silodosin assay

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ER E., ERK N.

JOURNAL OF ANALYTICAL SCIENCE AND TECHNOLOGY, vol.7, 2016 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 7
  • Publication Date: 2016
  • Doi Number: 10.1186/s40543-016-0100-y
  • Journal Name: JOURNAL OF ANALYTICAL SCIENCE AND TECHNOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: Silodosin, HPLC, Spectrofluorimetry, Determination, Validation
  • Ankara University Affiliated: Yes

Abstract

Background: A stability-indicating reversed-phase high-performance liquid chromatography (HPLC) method with a high sensitivity was developed for the determination of silodosin (SIL) in the presence of hydrochlorothiazide (HCT) as an internal standard.