Working principle and production techniques of the immunochromatographic card tests İmmünokromatografık kart testlerın çalişma prensıbı ve üretım teknıklerı

Kaya E., AKATA I., Bakırcı S., Dereli D., Küçükgüven E., Yılmaz İ.

Duzce Medical Journal, cilt.16, sa.3, ss.45-53, 2014 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16 Sayı: 3
  • Basım Tarihi: 2014
  • Dergi Adı: Duzce Medical Journal
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.45-53
  • Anahtar Kelimeler: Development of analytic test, Lateral flow immunoassay, Working principle of test
  • Ankara Üniversitesi Adresli: Evet

Özet

© 2012 Düzce Medical Journal.The lateral flow immunoassays have low cost, long shelf life, high precision and selectivity, a low detection limit. These tests can give quick results and are used all over the world. Lateral flow immunoassays can be used in wide area such as pregnancy test, drug screening tests, microbiological diagnostic tests and food safety tests. A person can see the results of these tests clearly with eyes so there is no need for any other analysis machine in order to see the results. These tests are usually used as a qualitative method but if we add most test lines that have different detection limits at the same test, we can obtain half quantitative tests. Antigen-antibody reactions that have a specificity are used mainly at these tests so their accuracy rates are over %98. There are two types as sandwich model and competitive model. A person that read this article can answer questions that “how a pregnancy test works?” or “how can we make a new lateral flow immunoassay?”. In addition we hope that this article can help people who try to do new lateral flow immunoassays. For our researches, this article is the first article about card tests in Turkish.