A Case of Nonsyndromic Unilateral Cleft Hand with Central Polydactyly, Syndactyly, and Thumb Hypoplasia: Support for a Common Etiology

Duran A., Buyukdogan H.

JOURNAL OF HAND AND MICROSURGERY, vol.11, no.3, pp.154-156, 2019 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 11 Issue: 3
  • Publication Date: 2019
  • Doi Number: 10.1055/s-0038-1669364
  • Journal Name: JOURNAL OF HAND AND MICROSURGERY
  • Journal Indexes: Emerging Sources Citation Index (ESCI)
  • Page Numbers: pp.154-156
  • Keywords: central polydactyly, cleft hand, syndactyly
  • Ankara University Affiliated: Yes

Abstract

Experimental studies showed that central polydactyly, syndactyly, and cleft hand might appear when the same teratogenic factor acts on embryos at the same developmental stage. These observations and some clinical cases support the concept that a common etiologic mechanism is involved in the development of these malformations. We report a clinical case that demonstrates the association previously observed in experimental studies. Here, a patient with unilateral nonsyndromic cleft hand, central polydactyly, first web syndactyly, osseous syndactyly between the ring and long fingers, and minor thumb hypoplasia was presented.