A Case of Nonsyndromic Unilateral Cleft Hand with Central Polydactyly, Syndactyly, and Thumb Hypoplasia: Support for a Common Etiology

Duran A., Buyukdogan H.

JOURNAL OF HAND AND MICROSURGERY, cilt.11, sa.3, ss.154-156, 2019 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 11 Sayı: 3
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1055/s-0038-1669364
  • Dergi Adı: JOURNAL OF HAND AND MICROSURGERY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
  • Sayfa Sayıları: ss.154-156
  • Anahtar Kelimeler: central polydactyly, cleft hand, syndactyly
  • Ankara Üniversitesi Adresli: Evet

Özet

Experimental studies showed that central polydactyly, syndactyly, and cleft hand might appear when the same teratogenic factor acts on embryos at the same developmental stage. These observations and some clinical cases support the concept that a common etiologic mechanism is involved in the development of these malformations. We report a clinical case that demonstrates the association previously observed in experimental studies. Here, a patient with unilateral nonsyndromic cleft hand, central polydactyly, first web syndactyly, osseous syndactyly between the ring and long fingers, and minor thumb hypoplasia was presented.