Naphthoquinones from the roots of Onosma argentatum Hub.-Mor. (Boraginaceae)
TURKISH JOURNAL OF CHEMISTRY, vol.28, no.4, pp.451-454, 2004 (SCI-Expanded, Scopus, TRDizin)
- Publication Type: Article / Article
- Volume: 28 Issue: 4
- Publication Date: 2004
- Journal Name: TURKISH JOURNAL OF CHEMISTRY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Page Numbers: pp.451-454
- Keywords: Onosma argentatum, natural naphthoquinones, shikonin derivatives, Boraginaccae, 5,8-O-dimethyl acetyl shikonin, ANTIMICROBIAL ACTIVITIES, PYRROLIZIDINE ALKALOIDS, DERIVATIVES
- Ankara University Affiliated: No
Abstract
Onosma argentatum Hub.-Mor. is an endemic species growing in Turkey. In this study, the roots of O. argentatum were extracted with n-hexane-dichloromethane (1:1). The extract was separated on a silica gel column eluting with n-hexane-ethyl acetate by gradient elution. New naphthoquinone compounds (3 known and 1 new) were isolated and their structures were elucidated by spectroscopic methods as deoxyshikonin, acetyl shikonin, 3-hydroxy-isovaleryl shikonin, and 5,8-O-dimethyl acetyl shikonin.