Hematopoietic Stem Cell Transplantation as Treatment for Patients with DOCK8 Deficiency

Aydin, Susanne; Freeman, Alexandra; Al-Herz, Waleed; Al-Mousa, Hamoud; Arnaout, Rand; Aydin, Roland; Barlogis, Vincent; Belohradsky, Bernd; Bonfim, Carmem; Bredius, Robbert; Chu, Julia; Ciocarlie, Oana; DOĞU, ESİN; Gaspar, Hubert; Geha, Raif; Gennery, Andrew; Hauck, Fabian; Hawwari, Abbas; Hickstein, Dennis; Hoenig, Manfred; İKİNCİOĞULLARI, KAMİLE; Klein, Christoph; Kumar, Ashish; Ifversen, Marianne; Matthes, Susanne; Metin, Ayse; Neven, Benedicte; Pai, Sung-Yun; Parikh, Suhag; Picard, Capucine; Renner, Ellen; Sanal, Ozden; Schulz, Ansgar; Schuster, Friedhelm; Shah, Nirali; Shereck, Evan; Slatter, Mary; Su, Helen; van Montfrans, Joris; Woessmann, Wilhelm; Ziegler, John; Albert, Michael

doi:10.1016/j.jaip.2018.10.035

Hematopoietic Stem Cell Transplantation as Treatment for Patients with DOCK8 Deficiency

Atıf İçin Kopyala

Aydin S. E., Freeman A. F., Al-Herz W., Al-Mousa H. A., Arnaout R. K., Aydin R. C., ...Daha Fazla

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, cilt.7, sa.3, ss.848-855, 2019 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 7 Sayı: 3
Basım Tarihi: 2019
Doi Numarası: 10.1016/j.jaip.2018.10.035
Dergi Adı: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.848-855
Anahtar Kelimeler: DOCK8 deficiency, HSCT, Combined immunodeficiency, DEDICATOR, IMMUNODEFICIENCY, PHENOTYPE, ADULTS, GRAFT
Ankara Üniversitesi Adresli: Evet

Özet

BACKGROUND: Biallelic variations in the dedicator of cytokinesis 8 (DOCK8) gene cause a combined immunodeficiency with eczema, recurrent bacterial and viral infections, and malignancy. Natural disease outcome is dismal, but allogeneic hematopoietic stem cell transplantation (HSCT) can cure the disease.