Synthesis and antimicrobial activity of some new 4-hydroxy-2H-1,4-benzoxazin-3(4H)-ones

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Ozden S., Ozturk A., GÖKER A. H., Altanlar N.

FARMACO, vol.55, no.11-12, pp.715-718, 2000 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 55 Issue: 11-12
• Publication Date: 2000
• Doi Number: 10.1016/s0014-827x(00)00098-7
• Journal Name: FARMACO
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Index Chemicus (IC)
• Page Numbers: pp.715-718
• Keywords: 4-hydroxy-2H-1,4-benzoxazin-3(4H)-one, antibacterial and antifungal activity, HYDROXAMIC ACID CONTENT, DERIVATIVES, GRAMINEAE, PLANTS, WHEAT
• Ankara University Affiliated: Yes

Abstract

Some 4-hydroxy-2H-1,4-benzoxazin-3(4H)-ones were synthesized and evaluated for their antimicrobial activities against Staphylococcus aureus, Escherichia coli and Candida albicans. Compounds 9, and 10 exhibited the best activity against Candida albicans. (C) 2000 Published by Elsevier Science S.A. All rights reserved.