Levels of F-2 isoprostane in Behcet's disease: Correlation with cardiometabolic risk factors

Sagun G., OĞUZ A., Mesci B., Isbilen B., Kavala M., KESKİN H., ...More

REDOX REPORT, vol.20, no.5, pp.223-227, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 5
  • Publication Date: 2015
  • Doi Number: 10.1179/1351000215y.0000000008
  • Journal Name: REDOX REPORT
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.223-227
  • Keywords: Behcet's disease, F-2 isoprostane, Cardiometabolic risk factors, CORONARY-ARTERY CALCIFICATION, SYSTEMIC-LUPUS-ERYTHEMATOSUS, OXIDATIVE STRESS, LIPID-PEROXIDATION, CARDIOVASCULAR-DISEASE, IN-VIVO, F-2-ISOPROSTANES, SCLERODERMA, F2-ALPHA, MARKERS
  • Ankara University Affiliated: No

Abstract

Objective: Behcet's disease (BD) is a chronic inflammatory disease and recent findings suggest a role of oxidative stress in the pathogenesis of BD. Free radical-induced oxidative stress is also involved in the pathogenesis of cardiovascular and other rheumatic diseases. Oxidative stress may be detected in vivo by measuring F-2 isoprostanes. Here, we measured plasma levels of F-2 isoprostane in patients with BD and evaluated the correlation of F-2 isoprostane with cardiometabolic risk factors.