Impact of chlorhexidine mouth rinse use on postextraction infection via nitric oxide pathway


ÖZMERİÇ KURTULUŞ N., Mollaoglu N., ELGÜN ÜLKAR S., DEVRİM E.

INFLAMMATION RESEARCH, cilt.59, sa.6, ss.437-441, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 59 Sayı: 6
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1007/s00011-009-0115-6
  • Dergi Adı: INFLAMMATION RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.437-441
  • Anahtar Kelimeler: Nitric oxide, Arginase, Chlorhexidine, Saliva, Gingiva, PERIODONTAL-DISEASE, GINGIVAL TISSUE, SYNTHASE, INHIBITION, EXPRESSION
  • Ankara Üniversitesi Adresli: Evet

Özet

Nitric oxide (NO) has been linked to inflammatory reactions, tissue destruction, host defense, and wound healing in oral diseases. It is known that arginase enzyme controls the synthesis of NO through arginine depletion. This study evaluated the arginase-NO pathway alteration in response to tissue injury after dental extraction surgery and the effect of postoperative use of 0.2% chlorhexidine gluconate rinse (CHX).