Electrooxidative behavior and determination of trifluoperazine at multiwalled carbon nanotube-modified glassy carbon electrode

DOĞAN TOPAL B.

Journal of Solid State Electrochemistry, cilt.17, sa.4, ss.1059-1066, 2013 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 4
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1007/s10008-012-1967-1
  • Dergi Adı: Journal of Solid State Electrochemistry
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1059-1066
  • Anahtar Kelimeler: Carbon nanotubes, Modified glassy carbon electrode, Pharmaceuticals, Trifluoperazine, Voltammetry
  • Ankara Üniversitesi Adresli: Evet

Özet

The mechanism of electrochemical oxidation of trifluoperazine has been proposed on the basis of cyclic and differential pulse voltammetry at a multiwalled carbon nanotube-modified glassy carbon electrode. The modified electrode exhibits catalytic activity, high sensitivity, and stability. The oxidation process exhibited an adsorption-controlled behavior. Also, depending on this adsorption control, a sensitive electroanalytical method for the determination of trifluoperazine has been investigated by adsorptive stripping differential pulse voltammetry. Under the optional conditions, the anodic peak current was linear to the trifluoperazine concentration over the range of 2.08 10-8 M to 1.67 10-6 M, and the limit of detection was 7.49 10-10 M. The modified electrode had good stability and repeatability, and it was successfully applied to the determination of trifluoperazine in pharmaceuticals. © 2012 Springer-Verlag Berlin Heidelberg.