The nondecussating pathway of the dentatorubrothalamic tract in humans: human connectome-based tractographic study and microdissection validation

Meola A., CÖMERT A., Yeh F., Sivakanthan S., Fernandez-Miranda J. C.

JOURNAL OF NEUROSURGERY, vol.124, no.5, pp.1406-1412, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 124 Issue: 5
  • Publication Date: 2016
  • Doi Number: 10.3171/2015.4.jns142741
  • Journal Name: JOURNAL OF NEUROSURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1406-1412
  • Keywords: dentate nucleus, red nucleus, fiber tractography, thalamus, fiber dissection, fiber tracts, anatomy, CEREBELLAR DENTATE NUCLEUS, ARM MOVEMENTS, MOTOR, ACTIVATION, MONKEY, STIMULATION, PARAMETERS, DISORDERS, RESPONSES, PATTERNS
  • Ankara University Affiliated: Yes

Abstract

OBJECTIVE The dentatorubrothalamic tract (DRTT) is the major efferent cerebellar pathway arising from the dentate nucleus (DN) and decussating to the contralateral red nucleus (RN) and thalamus. Surprisingly, hemispheric cerebellar output influences bilateral limb movements. In animals, uncrossed projections from the DN to the ipsilateral RN and thalamus may explain this phenomenon. The aim of this study was to clarify the anatomy of the dentatorubrothalamic connections in humans.