Application of carboxymethylcellulose in controlled drug release

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Atıf İçin Kopyala

Sungur S., EMREGÜL E.

JOURNAL OF MACROMOLECULAR SCIENCE-PURE AND APPLIED CHEMISTRY, cilt.A33, ss.319-325, 1996 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: A33
• Basım Tarihi: 1996
• Doi Numarası: 10.1080/10601329608020388
• Dergi Adı: JOURNAL OF MACROMOLECULAR SCIENCE-PURE AND APPLIED CHEMISTRY
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.319-325
• Ankara Üniversitesi Adresli: Evet

Özet

Controlled drug release was investigated by using Carboxymethylcellulose as carrier and erythromycin as model drug. Carboxymethylcellulose was chosen because of its biologically inert characteristics. It was crosslinked by ferric salts to obtain biodegradable beads. Controlled release was improved by coating with gelatin/caboxymethylcellulose and by crosslinking with ferric salts/chromium sulfate.