sEPCR Levels in Chronic Myeloproliferative Diseases and Their Association with Thromboembolic Events: A Case-Control Study

Atalay F., TOPRAK S. K., Koca E., Karakus S.

TURKISH JOURNAL OF HEMATOLOGY, cilt.31, sa.2, ss.121-127, 2014 (SCI-Expanded, Scopus, TRDizin) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 2
  • Basım Tarihi: 2014
  • Doi Numarası: 10.4274/tjh.2012.0150
  • Dergi Adı: TURKISH JOURNAL OF HEMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.121-127
  • Anahtar Kelimeler: Myeloproliferative disorders, Endothelial cell protein C receptor, Thrombosis, PROTEIN-C RECEPTOR, ESSENTIAL THROMBOCYTHEMIA, POLYCYTHEMIA-VERA, PLASMA-LEVELS, EPCR GENE, RISK-FACTOR, JAK2 V617F, THROMBOSIS, MUTATION, RESISTANCE
  • Ankara Üniversitesi Adresli: Evet

Özet

Objective: Venous, arterial, and microcirculatory events are frequently encountered in the clinical course of essential thrombocytosis and polycythemia vera. We aimed to investigate the levels of soluble endothelial protein C receptor (sEPCR) in myeloproliferative diseases to see whether there was a difference between the patients with and without history of thromboembolism.