A comparison of the in vitro cytotoxicity of two root canal sealers

Oztan M., Yilmaz S., Kalayci A., Zaimoglu L.

JOURNAL OF ORAL REHABILITATION, cilt.30, sa.4, ss.426-429, 2003 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 4
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1046/j.1365-2842.2003.01053.x
  • Dergi Adı: JOURNAL OF ORAL REHABILITATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.426-429
  • Anahtar Kelimeler: AH Plus, cytotoxicity, RSA, IN-VITRO, ASSAY
  • Ankara Üniversitesi Adresli: Evet

Özet

The purpose of this study was to compare the cytotoxicity of an epoxy resin-based sealer (AH Plus) and a silicone-based sealer (Roeko Seal Automix, RSA). Cytotoxicity was assessed using the MTT assay for mitochondrial enzyme activity and haemocytometer viable cell counting after 24, 48 and 72-h exposure to L929 cells. AH Plus and RSA showed no statistically significant difference in the degree of toxicity. Both sealers had a low toxic influence on the cells during the experimental period. This study indicates that epoxy resin-based sealer AH Plus and the silicone-based sealer RSA have similar levels of cytotoxicity to mouse fibroblasts.