Synthesis and antihyperglycemic activity of novel flavonyl 2,4-thiazolidinediones

Ertan R., Bozdag O.

Acta Pharmaceutica Turcica, vol.39, no.1, pp.33-37, 1997 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 39 Issue: 1
  • Publication Date: 1997
  • Journal Name: Acta Pharmaceutica Turcica
  • Journal Indexes: Scopus, International Pharmaceutical Abstracts
  • Page Numbers: pp.33-37
  • Keywords: 2,4-thiazolidinediones, antihyperglycemic activity, flavonyl-2,4-thiazolidinediones
  • Ankara University Affiliated: Yes

Abstract

In this study, novel flavonyl-2,4-thiazolidinediones were synthesized. These compounds were obtained by linking the flavone and the 2,4-thiazolidinedione rings up using a methylene and/or a methylene groups. Their chemical structures have been elucidated by IR, 1H-NMR, Mass spectra and elementary analysis. Furthermore, the synthesized compounds are under investigation for antihyperglycemic activity.