Ischemia-modified albumin and cardiovascular risk markers in polycystic ovary syndrome with or without insulin resistance

Caglar G. S., Oztas E., Karadag D., Pabuccu R., Demirtas S.

Fertility and Sterility, cilt.95, sa.1, ss.310-313, 2011 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 95 Sayı: 1
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1016/j.fertnstert.2010.06.092
  • Dergi Adı: Fertility and Sterility
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.310-313
  • Anahtar Kelimeler: cardiovascular risk, insulin resistance, ischemia modified albumin, Ovary syndrome
  • Ankara Üniversitesi Adresli: Evet

Özet

The aim of this study was to evaluate ischemia-modified albumin levels (IMA) in polycystic ovary syndrome (PCOS) cases with and without insulin resistance and the correlation of IMA with carotid intima media thickness, homocysteine, and high-sensitivity C-reactive protein levels. Significantly higher levels of IMA in young lean PCOS cases, more relevant in insulin resistant cases, indicates chronic hypoxia and oxidative stress which might play a role in the metabolic consequences in PCOS. © 2011 American Society for Reproductive Medicine, Published by Elsevier Inc.