Effect of inhibition of ornithine decarboxylase activity in a model of acute hepatocellular necrosis

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Yurdaydin C., Swain M., Mininberg E., Vergalla J., Kleiner D., Paul S., ...Daha Fazla

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, cilt.10, sa.6, ss.503-507, 1998 (SCI-Expanded, Scopus)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 10 Sayı: 6
• Basım Tarihi: 1998
• Doi Numarası: 10.1097/00042737-199806000-00012
• Dergi Adı: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.503-507
• Anahtar Kelimeler: hepatic encephalopathy, thioacetamide, polyamines, ornithine, ACUTE LIVER-FAILURE, HEPATIC-ENCEPHALOPATHY, RAT-LIVER, ALPHA-DIFLUOROMETHYLORNITHINE, POLYAMINE METABOLISM, ALCOHOLIC HEPATITIS, NITRIC-OXIDE, REGENERATION, AMINOTRANSFERASE, PUTRESCINE
• Ankara Üniversitesi Adresli: Hayır

Özet

Objective The effect of blockade of the enzyme ornithine decarboxylase by difluoromethylornithine (DFMO) on hepatocellular necrosis and survival in rats treated with thioacetamide (TAA) was investigated.