Adsorptive stripping voltammetric determination of midazolam as a method for quality control

KIR S., Onar A., Temizer A.

Analytica Chimica Acta, cilt.229, sa.C, ss.145-147, 1990 (SCI-Expanded, Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 229 Sayı: C
  • Basım Tarihi: 1990
  • Doi Numarası: 10.1016/s0003-2670(00)85120-x
  • Dergi Adı: Analytica Chimica Acta
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.145-147
  • Ankara Üniversitesi Adresli: Hayır

Özet

Controlled interfacial accumulation of the benzodiazepine midazolam at a hanging mercury drop electrode provides the basis for a highly sensitive and accurate adsorptive stripping voltammetric procedure. The response was linear in the range 1.9 × 10-6- × 10-9 M when using a 120-s preconcentration at -0.45 V vs. Ag/AgCl in Britton-Robinson buffer of pH 5.00. In this range the relative standard deviation was between 1.21 and 1.62%. The applicability of the method to pharmaceutical preparations is discussed. © 1990.