Detection and characterization of Distemper virus in a mink (Neovison vison) in Turkey

Oğuzoğlu T. Ç., Yücel Tenekeci G., Çalışkan M., Bozkurt M. F.

VETERINARIA ITALIANA, vol.54, no.1, pp.79-85, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 54 Issue: 1
  • Publication Date: 2018
  • Doi Number: 10.12834/vetit.936.4787.4
  • Journal Name: VETERINARIA ITALIANA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.79-85
  • Keywords: Canine distemper virus, Haemagglutinin and, fusion genes, Mink, Turkey, CANINE-DISTEMPER, DOGS, HEMAGGLUTININ, PATHOGENESIS, CARNIVORES, FOXES, GENE
  • Ankara University Affiliated: Yes

Abstract

In this study a mink showing hard pad disease like symptoms was euthanised. Heart blood and various tissue samples collected during necroscopy and tested by specific RT-PCR were found positive for CDV. H and F gene segments of the CDV strain was also partially sequenced using the appropriate primers, and subsequently the sequences were analysed and compared with same gene fragment sequence of other CDV isolates from different countries. The results of the phylogenetic analysis showed that the Turkish-Mink distemper strain is closely related to European CDV strains of lineage 1. Additionally, the distemper antigen was also detected when the tissue samples were examined by histology or immunohistochemistry.