Cutaneous, pulmonary and hepatic sarcoidosis associated with autoimmune complications during interferon-alpha treatment for hepatitis C virus infection


Akay B. N., Ekmekci P., Sanli H., Celik G., Bozdayi M.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, cilt.20, sa.4, ss.442-445, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 4
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1111/j.1468-3083.2006.01450.x
  • Dergi Adı: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.442-445
  • Anahtar Kelimeler: chronic hepatitis C, interferon-alpha, sarcoidosis, CHRONIC MYELOGENOUS LEUKEMIA, LUNG LYMPHOCYTES-T, ALVEOLAR MACROPHAGES, THERAPY, THROMBOCYTOPENIA, GAMMA, PATIENT, RELEASE, CELLS
  • Ankara Üniversitesi Adresli: Evet

Özet

A patient with hepatitis C virus (HCV) infection was diagnosed with cutaneous, pulmonary and hepatic sarcoidosis following interferon alpha therapy. There are only a few cases of sarcoidosis associated with this treatment. This is the first case who not only developed sarcoidosis, but also autoimmune hypothyroidism and thrombocytopenia during interferon alpha therapy due to the immunomodulatory effects of the drug.