Synthesis and antimicrobial activity of some new thiazolyl thiazolidine-2,4-dione derivatives

Bozdag-Duendar O., Oezgen O., Mentese A., Altanlar N., Atli O., Kendi E., ...Daha Fazla

BIOORGANIC & MEDICINAL CHEMISTRY, cilt.15, sa.18, ss.6012-6017, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 18
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.bmc.2007.06.049
  • Dergi Adı: BIOORGANIC & MEDICINAL CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.6012-6017
  • Anahtar Kelimeler: thiazolidine-2,4-diones, thiazole derivatives, antimicrobial activity, single-x-ray structure, IN-VITRO, METHICILLIN-RESISTANT, ANTIBIOTICS, BINDING
  • Ankara Üniversitesi Adresli: Evet

Özet

In this study, a series of thiazolyl thiazolidine-2,4-dione derivatives (Va-f and Vla-f) were synthesized and evaluated for their antibacterial and antifungal activities against Staphylococcus aureus (ATCC 25923), methicillin resistant S. aureus (MRSA ATCC 43300), methicillin resistant S. aureus (MRSA isolate), and Escherichia coli (ATCC 23556) and C. albicans (ATCC10145). All the compounds were found active against used microorganisms. (c) 2007 Elsevier Ltd. All rights reserved.