The Effect of CYP1A1 and GSTP1 Isozymes on the Occurrence of Aortic Aneurysms

Simsek E., KILIÇ M., Simsek G., OĞUZTÜZÜN S., Moran B., Saritas A., ...Daha Fazla

THORACIC AND CARDIOVASCULAR SURGEON, cilt.63, sa.2, ss.152-157, 2015 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 63 Sayı: 2
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1055/s-0034-1367735
  • Dergi Adı: THORACIC AND CARDIOVASCULAR SURGEON
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.152-157
  • Anahtar Kelimeler: aortic aneurysm, aorta/aortic, artery/arteries, coronary bypass surgery, CYP1A1, GSTP1, vascular disease, OCCLUSIVE DISEASE, OXIDATIVE STRESS, NITRIC-OXIDE, PEROXYNITRITE, EXPRESSION, TRANSFERASES, INACTIVATION
  • Ankara Üniversitesi Adresli: Evet

Özet

Background Aortic aneurysms are vascular diseases that are associated with high mortality and morbidity. Cytochrome P450 CYP1A1 and glutathione S-transferase (GSTP1) isozymes were searched and compared with the patients who had experienced aortic surgery due to aortic aneurysm and atherosclerotic patients without aneurysm to find the relation of the oxidative stress with the aneurysms.