Akademik Veri Yönetim Sistemi
5th International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2022), Ankara, Türkiye, 23 - 25 Kasım 2022, ss.1
A bioinsecticide called spinosad is commonly used for control of insect pests. This insecticide affects both target organisms (insects) and non-target organisms (indirectly human and other vertebrates). While spinosad neutralizes insects, humans are also affected by this substance if there is accidental contamination. Therefore, rats in the mammal group, including humans, were used as model in experiments. The rats used in the experiments were divided into 14 groups. Two were determined as the control group, six were determined as the spinosad applied group, and six were determined as the Spinosad + Vitamin E applied group. Spinosad applied rats were then sacrificed under ether anesthesia after 24 h, 72 h, and 1 week, and liver tissues were collected from these rats. Tissue samples were examined in a light microscope with Hematoxylin-Eosin staining and in a fluorescence microscope with DAPI staining. This study showed that spinosad has detrimental impacts on the liver cellular structure.