Mixed chimerism following hematopoietic stem cell transplantation in pediatric thalassemia major patients: a single center experience
TURKISH JOURNAL OF HEMATOLOGY, cilt.27, sa.1, ss.8-14, 2010 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 27 Sayı: 1
- Basım Tarihi: 2010
- Dergi Adı: TURKISH JOURNAL OF HEMATOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.8-14
- Anahtar Kelimeler: Thalassemia major, mixed chimerism, pediatrics, chimerism, hematopoietic stem cell transplantation, non-malignant, BONE-MARROW-TRANSPLANTATION, BETA-THALASSEMIA, CHILDREN, GRAFT, RELAPSE, BLOOD
- Ankara Üniversitesi Adresli: Evet
Özet
Objective: Stable mixed chimerism (MC) may result in cure for thalassemia major patients following hematopoetic stem cell transplantation (HSCT), but rejection can occur. Twenty-eight HSCTs for thalassemia major were reviewed retrospectively to evaluate the clinical course of MC with possible risk factors and predictors of outcome, with a median follow-up of 1669 days (811-3576 days).