Isolation and quantification of alantolactone/isoalantolactone from the roots of Inula helenium subsp. Turcoracemosa Inula helenium subsp. turcoracemosa köklerinden alantolakton/İzoalantolakton İzolasyonu ve miktar tayini
Turkish Journal of Pharmaceutical Sciences, cilt.10, sa.3, ss.447-452, 2013 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 10 Sayı: 3
- Basım Tarihi: 2013
- Dergi Adı: Turkish Journal of Pharmaceutical Sciences
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.447-452
- Anahtar Kelimeler: Alantolactone/isoalantolactone, Inula helenium subsp, RP-HPLC, Turcoracemosa
- Ankara Üniversitesi Adresli: Evet
Özet
Alantolactone/isoalantolactone, a mixture of isomeric sesquiterpene compounds, was isolated from the roots of Inula helenium L. subsp. turcoracemosa Grierson and its amount was quantified by RP-HPLC. The structure of alantolactone/isoalantolactone was elucidated by using HPLC and 1NMR data. Alantolactone/isoalantolactone was found in serious amount in the roots of the plant as 1.6338 ± 0.0198 % (w/w). The roots of Inula helenium subsp. turcoracemosa growing in Turkey were found rich in this isomeric pair known to be strong antiproliferative and antimicrobial agent.