Isolation and quantification of alantolactone/isoalantolactone from the roots of Inula helenium subsp. Turcoracemosa Inula helenium subsp. turcoracemosa köklerinden alantolakton/İzoalantolakton İzolasyonu ve miktar tayini

GÖKBULUT A., Şarer E.

Turkish Journal of Pharmaceutical Sciences, cilt.10, sa.3, ss.447-452, 2013 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 10 Sayı: 3
  • Basım Tarihi: 2013
  • Dergi Adı: Turkish Journal of Pharmaceutical Sciences
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.447-452
  • Anahtar Kelimeler: Alantolactone/isoalantolactone, Inula helenium subsp, RP-HPLC, Turcoracemosa
  • Ankara Üniversitesi Adresli: Evet

Özet

Alantolactone/isoalantolactone, a mixture of isomeric sesquiterpene compounds, was isolated from the roots of Inula helenium L. subsp. turcoracemosa Grierson and its amount was quantified by RP-HPLC. The structure of alantolactone/isoalantolactone was elucidated by using HPLC and 1NMR data. Alantolactone/isoalantolactone was found in serious amount in the roots of the plant as 1.6338 ± 0.0198 % (w/w). The roots of Inula helenium subsp. turcoracemosa growing in Turkey were found rich in this isomeric pair known to be strong antiproliferative and antimicrobial agent.