Dipyrone increases the blood flow of arterial dorsal skin flaps

Gulmez S. E., Serel S., Uluc A., CAN Z., Ergun H.

AESTHETIC PLASTIC SURGERY, cilt.32, sa.5, ss.766-770, 2008 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 5
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1007/s00266-008-9126-x
  • Dergi Adı: AESTHETIC PLASTIC SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.766-770
  • Anahtar Kelimeler: dipyrone (metamizole), dorsal skin flap, flap survival, laser Doppler, THERAPY ENHANCES EXPRESSION, KAPPA-B GENE, DELAY PHENOMENON, SIGNAL PATHWAYS, ISCHEMIC FLAPS, BFGF GENES, SURVIVAL, RAT, MODEL, VASOSPASM
  • Ankara Üniversitesi Adresli: Evet

Özet

Background Findings have shown that dipyrone has a beneficial effect on skin flap survival. A pharmacologic explanation for this effect points to its vascular smooth muscle-relaxing effect. This study evaluated the effect of dipyrone on blood flow and thus survival of rat random dorsal skin flaps.