The Effects of Androgens on Cardiometabolic Syndrome: Current Therapeutic Concepts

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Kirlangic Ö. F., Yılmaz Oral D., Kaya Sezginer E., Toktanis G., Tezgelen A. S., Sen E., ...Daha Fazla

SEXUAL MEDICINE, cilt.8, sa.2, ss.132-155, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 8 Sayı: 2
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.esxm.2020.02.006
  • Dergi Adı: SEXUAL MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, Directory of Open Access Journals
  • Sayfa Sayıları: ss.132-155
  • Anahtar Kelimeler: Testosterone, Cardiometabolic Syndrome, Androgen Receptors, Type 2 Diabetes Mellitus, Hypogonadism, Androgen Replacement Therapy, TESTOSTERONE REPLACEMENT THERAPY, LEFT-VENTRICULAR MASS, CARDIOVASCULAR RISK-FACTORS, AMBULATORY BLOOD-PRESSURE, LOW SERUM TESTOSTERONE, 3RD NATIONAL-HEALTH, SPINAL-CORD-INJURY, METABOLIC SYNDROME, BODY-COMPOSITION, HYPOGONADAL MEN
  • Ankara Üniversitesi Adresli: Evet

Özet

Introduction: Cardiometabolic syndrome (CMS), as a bunch of metabolic disorders mainly characterized by type 2 diabetes mellitus (T2DM), hypertension, atherosclerosis, central adiposity, and abdominal obesity triggering androgen deficiency, is one of the most critical threats to men. Although many significant preclinical and clinical findings explain CMS, new approaches toward common pathophysiological mechanisms and reasonable therapeutic targets are lacking.